Mediastinal diffuse large B cell lymphoma

Case contributed by Dr Henry Knipe

Presentation

Shortness of breath and tachycardic.

Patient Data

Age: 30 years
Gender: Male

Chest

X-ray

Superior mediastinal mass with tracheal deviation to the right and left hilar lobulated mass, suggestive of lymphadenopathy - this should be further assessed with CT. Lungs and pleural spaces are clear. No bony abnormality. No free subdiaphragmatic gas.

No evidence of pulmonary embolism. Extensive mediastinal and hilar lymphadenopathy leading to significant effacement of the bronchovascular structures at both hila, most extensively involving the right main pulmonary artery and left main stem bronchus.

Case Discussion

US-guided biopsy was subsequently performed on the superior mediastinal mass. 

Histopathology:

DIAGNOSIS: Mediastinal mass biopsy: Non-Hodgkins B-cell lymphoma, morphologically consistent with diffuse large B-cell lymphoma.

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