Medulloblastoma

Case contributed by Dr Mustafa Takesh

Presentation

Headaches increasing in severity for longer than 1 month, nausea and dizziness.

Patient Data

Age: 30 years
Gender: Male
CT

Selected CT images demonstrating a posterior fossa mass, centered in the upper portion of the vermis containing cystic and solid components with significant effacement of the forth ventricle and diffuse dilatation of the supratentorial ventricles.

MRI

Predominantly solid mass arising from the vermis with cystic components and restricted diffusion.

There is a marked mass effect, including effacement of the fourth ventricle and infratentorial CSF cisterns with low-lying cerebellar tonsils.   

Post surgical MRI

MRI

Expected postsurgical changes following recent resection of the posterior fossa mass. Right transparietal approach shunt in appropriate position. 

Case Discussion

Classic features of medulloblastoma, histologically confirmed as SHH-activated and TP53 Wildtype (WHO grade IV). 

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