Medulloblastoma - adult

Case contributed by Bahman Rasuli
Diagnosis certain

Presentation

Ataxia, gait disturbance, and vertigo for a few weeks.

Patient Data

Age: 30 years
Gender: Male
mri

Large solid mass located centrally within the posterior fossa with mild vasogenic edema. It is high T2 signal and low T1 signal with marked water restriction on DWI images

No normal vermis can be identified and the mass is likely to arise from it

Minimal pressure effect on the fourth ventricle 

Another similar smaller mass at the right cerebellar hemisphere superior part shows water restriction on DWI images.

mri

Post-treatment changes as:

Diffuse pachymeningeal enhancement

Malacic changes surrounded by gliosis and hemosiderin rim along the cerebellar vermis and right cerebellar hemisphere 

Two abnormal signal areas ( high on T1 and iso signal on T2 ) at the right cerebellar hemisphere and cerebellar vermis due to hematoma on subacute phase

Right lateral ventricle VP shunt

A few high signal foci in T2 and flair sequences at subcortical and periventricular white matter of both cerebral hemispheres depict microvascular ischemic events.

Photo

Desmoplastic/nodular medulloblastoma, WHO grade IV.

Case Discussion

The imaging features are typical of medulloblastoma with high cellularity accounting for diffusion restriction. The diagnosis was confirmed histologically. 

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