Medulloblastoma in pregnancy

Case contributed by Dr Saeed Soltany Hosn


A 19-year-old female in her 17th week of pregnancy was presented with a severe acute headache. Her past medical history was unremarkable.Due to the case's pregnancy, MRI was done instead of CT scan.

Patient Data

Age: 19 Y/O
Gender: Female

The MRI reveales a well defined heterogenous lobulated mass  which is hypo to isointense on T1 WI and slightly hyperintense on T2WI, with mild perilesional edema and a marked  hetergenous contrast enhancement in the right cerebellar hemisphere. There is also marked dilatation of the lateral ventricles including the temporal horns and bowing of the corpus callosum indicating obstructive tetra-ventricular  hydrocephalus. There is also  some degree of trans ependymal migration of csf  surrounding the ventricles on T2/FLAIR sequence. Extra-axial CSF spaces  are not distended . Note the mild lepthomeningeal enhancement. Also, note the inferior herniation of the cerebellar tonsils, bilateral optic nerve sheath dilation,  and acquired chiari, are resulted in the mass effect of the tumor. Opacification of  the left maxillary and sphenoid sinuses are incidental findings.



The postoperative CT scan reveals the evidence of craniotomy and a decrease of pressure effect. 

Case Discussion

She underwent termination of pregnancy prior to craniotomy. Surgical pathology confirmed the case as medulloblastoma.

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Case information

rID: 33230
Published: 4th Jan 2015
Last edited: 25th Nov 2015
Inclusion in quiz mode: Included

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