Melorheostosis

Case contributed by Dr Eduardo Santiago Lopez

Presentation

45 year old male with chronic calf pain.

Patient Data

Age: 45
Gender: Male
Modality: X-ray

The principal findings in this images are cortical irregular thickening of fibula that causes narrowing of the medullary space.

Linear periosteal thickening of the proximal and posterior tibia resembling dripping wax, that correlates with the patient's site of pain.

Case Discussion

Melorheostosis is a benign sclerosing bone dysplasia, characterized clinically by chronic pain and soft-tissue contractures when symptomatic. The presentation could be monostotic, polyostotic or monomelic, mainly lower limb. This entity has been related to a functional loss mutation in the LEMD3 gene, as well as osteopoikilosis. Imaging findings include linear or curvilinear cortical thickening in tubular bones resembling candle melting wax. In this case, the patient presented chronic calf pain.

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Case Information

rID: 51552
Case created: 25th Feb 2017
Last edited: 10th Mar 2017
Inclusion in quiz mode: Excluded

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