Known Case of AML followed by CML with non specific headache. A contrast enhancement CT (not shown) was done which was reported as a falcine meningioma. MRI to further assess.
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-Meningeal leukemia occurs in upto 1/3 of cases with Leukemia
-more common in childhood than adults, especially kids with ALL who relapse after combination chemo
-more common with Lymphocytic than myelogenous leukemia
- cranial irradiation with intrathecal methotrexate is treatment of choice, however it gives rise to a methotrexate associated necrotising encephalopathy in some patients.
- Adams and Victor's principles of neurology By Allan H. Ropper, Raymond Delacy Adams, Maurice Victor, Robert H. Brown