Meningeal leukaemia

Case contributed by Dr Prashant Gupta

Presentation

Known Case of AML followed by CML with non specific headache. A contrast enhancement CT (not shown) was done which was reported as a falcine meningioma. MRI to further assess.

Patient Data

Age: 55
Gender: Female
MRI

Case Discussion

-Meningeal leukemia occurs in upto 1/3 of cases with Leukemia

-more common in childhood than adults, especially kids with ALL who relapse after combination chemo

-more common with Lymphocytic than myelogenous leukemia

- cranial irradiation with intrathecal methotrexate is treatment of choice, however it gives rise to a methotrexate associated necrotising encephalopathy in some patients.

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Case information

rID: 17272
Case created: 31st Mar 2012
Last edited: 15th Dec 2015
Inclusion in quiz mode: Included

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