Case contributed by A.Prof Frank Gaillard


Personality change.

Patient Data

Age: 50 years
Gender: Male

There is large anterior cranial fossa extra axial mass separated from the displaced frontal lobes by a prominent CSF cleft, and small left sided peritumoural cysts measuring up to centimeter in depth. The mass demonstrates prominent contrast enhancement and fills the olfactory grooves bilaterally, and possibly extends a little into the roof of the nasal cavity. Posteriorly the mass extends to the pituitary fossa, into which extends a small tongue of tissue. It also extends above the optic nerves just as that enter the optic canals bilaterally, more so on the left. The left optic nerve appears distorted by the mass and inferiorly displaced. There is no convincing evidence of extension into the orbits. Extensive T2 high signal in the white matter of the frontal lobes is indicative of edema, with prominent white matter buckling. The mass distorts the frontal horns of the lateral ventricles, with a degree of obstruction to outflow, more marked on the left, with the ventricle appearing dilated and a small amount of transependymal edema noted. 

The anterior cerebral arteries are displaced posterosuperiorly. MRA is unremarkable otherwise, with no intracranial abnormality identified.The remainder of the brain is unremarkable. Note is made of quite prominent frontal sinus pneumatization


Large anterior cranial fossa meningioma displacing anterior cerebral arteries postero-superiorly.

Case Discussion

Patient went on to have surgery.


MICROSCOPIC DESCRIPTION: Paraffin sections show a moderately hypercellular meningioma with a well developed syncytial architecture. Tumor cells have uniform nuclear features. No mitotic figures or areas of necrosis are identified and there is no evidence of brain invasion.

FINAL DIAGNOSIS: Bifrontal olfactory groove meningioma

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Case information

rID: 42875
Published: 14th Feb 2016
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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