Meningioma - volcano sign

Case contributed by A.Prof Frank Gaillard



Patient Data

Age: 25 years
Gender: Female

There is a large extra-axial solid tumor within the left frontotemporal region compressing the adjacent brain parenchyma, which shows a small rim of edema and causing an 8 mm rightward midline shift and mild left uncal herniation. It has a heterogeneous signal intensity that is predominantly low on both T1 and T2 weighted images, showing vivid and intense contrast enhancement. The lesion is durally broad-based with signs of associated bone hyperostosis.

A posterosuperior lobulated extra-axial tumor, although showing a different signal pattern and less vivid enhancement, is felt part of the same process.

There is a 10mm right postcentral gyrus cavernous malformations is noted.

Conclusion: features are those of two, probably connected, left-sided meningiomas. 

Case Discussion

Although radiology probably has enough named signs, I think this appearance warrants a new one. The volcano sign! It represents the triangular hyperostosis often seen at the site of initial growth of a meningioma, which coincides with the intratumoral vascularity (sunburst sign or spoke wheel sign). 

When viewed side on, the hyperostosis and tumoral flow-voids are reminiscent of an exploding volcano. 

The patient went on to have a resection of both masses. 


First larger lesion: paraffin sections show a moderately cellular dural-based tumor. This is composed of spindle cells arranged intersecting fasciculi within a dense hyalinised fibrous stroma. Tumor cells show mild nuclear pleomorphism. No mitotic figures or areas of necrosis are seen. There is no evidence of brain invasion.

Second smaller lesion: paraffin sections show a moderately cellular meningioma. This has well-developed syncytial architecture. Tumor cells have uniform nuclear features. No mitotic figures or areas of necrosis are identified.

Immunohistochemistry results show tumor cells stain EMA+, PgR-, SSTR2a+ and STAT6-.

FINAL DIAGNOSIS: meningioma (WHO Grade I).

PlayAdd to Share

Case information

rID: 62685
Published: 13th Sep 2018
Last edited: 13th Sep 2018
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.