Mesial temporal sclerosis with incomplete inversion (left)

Case contributed by Dr Derek Smith


Complex partial seizures with déjà vu episodes, speech disturbance, and stereotyped motor episodes.

Patient Data

Age: 25 years
Gender: Female

Small left hippocampal head and body with abnormal architecture, best demonstrated on the coronal T2w sequence. Subtle increased T2w/FLAIR signal.

No migrational abnormality or mass lesion.


Manipulated images

Zoomed and annotated coronal T2w sequence follows the left (yellow) and right (red) collateral sulci. At the mesial temporal lobe, the left collateral sulcus is too vertical, consistent with incomplete inversion of the hippocampus.

Case Discussion

Close inspection of the coronal T2w sequence shows not only atrophy and abnormal internal architecture of the left hippocampus, but also an abnormally vertical left collateral sulcus. This "incomplete inversion" of the hippocampus is in itself a potential epileptogenic focus.

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Case information

rID: 56216
Case created: 18th Oct 2017
Last edited: 18th Oct 2017
Tag: 3t
Inclusion in quiz mode: Included

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