Methanol poisoning

Case contributed by Hidayatullah Hamidi
Diagnosis certain


Previously healthy young man, presented with acute onset of confusion and headache for last two days after consuming alcohol.

Patient Data

Age: 20 years
Gender: Male

Bilateral putaminal hemorrhagic necrosis evident by high signal on T1WI, T2WI and FLAIR sequence with drop out signal on T2* GRE and diffusion restriction.

Case Discussion

Fraudulent adulteration of wine is the common cause of acute methanol intoxication in developing countries. The Putamina are the most susceptible sites for damage in methanol intoxication, other hallmarks to be aware of are include diffuse hypo-attenuation in cerebral white matter and hemorrhages.

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