Microcystic meningioma

Case contributed by A.Prof Frank Gaillard

Presentation

Headache

Patient Data

Age: 50 years
MRI

A  lobulated extra-axial mass is present indenting the left frontal lobe. It is of high T2 signal and demonstrates vivid enhancement except for areas of cystic change. 

Case Discussion

The patient went on to have surgery.

Histology

MICROSCOPIC DESCRIPTION: Sections show a dural-based tumour composed of variably sized thin-walled blood vessels, microcysts and intervening stroma containing tumour cells with abundant eosinophilic cytoplasm, round to oval nuclei with fine chromatin and inconspicuous nucleoli. No necrosis or mitoses are seen. No brain invasion is identified. There is no evidence of malignancy.

Immunohistochemical results show tumour cells stain: EMA weak+, PR+, Inhibin- and Topoisomerase 5-8%.

FINAL DIAGNOSIS: microcystic meningioma (WHO Grade I).

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Case information

rID: 51464
Case created: 17th Feb 2017
Last edited: 30th May 2017
Inclusion in quiz mode: Included

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