Received radiotherapy (17 sessions) post-surgical resection of a posterior fossa medulloblastoma.
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Bilateral dystrophic calcifications at the corticomedullary junction in the posterior temporal and occipital lobes, the lentifrom nuclei and the lateral aspect of both thalamus.
Lacunar infart in the deep right parietal white matter.
Ventricular shunt at the frontal horn.
1 case question available
Mineralizing microangiopathy is one of the complications of cranial radiotherapy, consist of late sequelae with typical dystrophic calcifications at the corticomedullary junction, lentiform nuclei and the dentate nucleus. In this pediatric case with a previous resection of medulloblastoma, those are more evident at the posterior temporal and occipital lobes.
Differential diagnosis includes Fahr's Syndrome (e.g. hyperparathyroidism, hypoparathyroidism, pseudohypoparathyroidism) and cortical laminar necrosis.
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