Mixed germ cell tumor of the testis (gross pathology)

Case contributed by A.Prof Frank Gaillard


Right groin pain for few weeks.

Patient Data

Age: 30 years
Gender: Male

Mixed germ cell tumor of the testis

1. Embryonal cell carcinoma.
2. Teratoma.
3. Seminoma.

Image courtesy of Dharam Ramnani. Please see case description page for licence and original file information. 

Case Discussion

The patient was initially treated with antibiotics by his primary care physician but groin fullness and swelling persisted.

Testicular ultrasound showed multiple intratesticular masses consistent with malignancy. CT of chest, abdomen and pelvis done prior to inguinal orchiectomy revealed retroperitoneal lymphadenopathy most consistent with metastases from his testicular cancer. Serum tumor markers showed normal AFP and beta-hCG and elevated LDH.

Right inguinal orchiectomy specimen showed a mixed germ cell tumor consisting of embryonal carcinoma, seminoma, and teratoma.

The teratoma component had mostly immature elements - highly cellular primitive-appearing stroma, embryonic tubules, and foci of neuroepithelium.

Author: Dharam Ramnani

Original file: Flick http://www.flickr.com/photos/dramnani/4770938343/

Modifications: square crop - added blue background to bottom of image

License: Reproduced here with permission. All rights reserved by the author.

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Case information

rID: 11093
Published: 16th Oct 2010
Last edited: 1st Feb 2019
Inclusion in quiz mode: Included

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