Mixed germ cell tumor of the testis (gross pathology)

Case contributed by Assoc Prof Frank Gaillard

Presentation

Right groin pain for few weeks.

Patient Data

Age: 30 years
Gender: Male

Orchiectomy. Mixed germ cell tumor of the testis consisting of: 

  1. embryonal cell carcinoma
  2. teratoma (mostly immature elements - highly cellular primitive-appearing stroma, embryonic tubules, and foci of neuroepithelium)
  3. seminoma

Image courtesy of Dharam Ramnani.

Original file: Flick http://www.flickr.com/photos/dramnani/4770938343/

Modifications: square crop - added blue background to bottom of the image

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Case Discussion

The patient was initially treated with antibiotics by his primary care physician but groin fullness and swelling persisted.

Testicular ultrasound showed multiple intratesticular masses consistent with malignancy. CT of chest, abdomen and pelvis done prior to inguinal orchiectomy revealed retroperitoneal lymphadenopathy most consistent with metastases from his testicular cancer. Serum tumor markers showed normal AFP and beta-hCG and elevated LDH.

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