Mönckeberg medial calcific sclerosis

Case contributed by Ke Chen
Diagnosis almost certain

Presentation

Incidental finding in a patient with advanced diabetes and chronic renal disease.

Patient Data

Age: 40 years
Gender: Female

Circumferential extensive calcification of the arteries of the upper limb.

Case Discussion

The patient was known for a long history of uncontrolled type I diabetes and had recently developed terminal renal failure.

The extensive calcifications shown are highly characteristic of Mönckeberg sclerosis, which represent medial calcification of medium and small muscular arteries associated with diabetes and renal failure.

In contrast to atherosclerotic disease, Mönckeberg sclerosis does not cause luminal obstruction.

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