Multicentric glioblastoma

Case contributed by Ian Bickle
Diagnosis almost certain

Presentation

5 week history of headache. Now confusion and left foot drop/leg weakness. SOL or CVA?

Patient Data

Age: 60 years
Gender: Male
ct
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Info

Right frontal lobe mass infiltrating the corpus callosum and crossing the midline.

At least two smaller similar left frontal lesions.

Significant perilesional white matter oedema with respect to both lesions and in the right parietal lobe near the vertex.

mri
This study is a stack
Axial
T2
This study is a stack
Axial
T1
This study is a stack
Axial
FLAIR
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Axial
ADC
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Axial
DWI
This study is a stack
Axial
T1 C+
This study is a stack
T1
C+
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Info

4.9cm right frontal irregular ring enhancing lesion infiltrating the corpus callosum.

1.2cm right parietal and multiple morphologically similar left frontal lesions, the largest 5.6cm.

Significant perilesional white matter oedema.

Case Discussion

This a case of multicentric glioblastoma - there is no communication or altered MR signal between the largest butterfly component and the other lesions in the cerebral hemispheres.

It is therefore the less common multicentric rather than multifocal subtype.

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