Multicystic encephalomalacia

Case contributed by Mustafa Abdalla Eltierifi
Diagnosis certain

Presentation

History of birth asphyxia, hypotonia, developmental delay and seizures

Patient Data

Age: 3 years
Gender: Male
mri

Reduced volume of both cerebral hemispheres with multi-cystic areas of various sizes seen within the cortex and white matter.

Dilated supra-tentorial ventricular system and atrophy of the corpus callosum. Basal ganlia and posterior fossa are preserved.

Case Discussion

Multicystic encephalomalacia is a sequela of a diffuse brain ischemic insult as in this case.  The cysts resulting from the destruction of the cerebral white matter and the linear septae represent glial cells with some viable neurons.

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