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Multinodular and vacuolating neuronal tumor

Case contributed by Maxime St-Amant
Diagnosis almost certain

Presentation

Recent onset of seizures. Rule out structural abnormality.

Patient Data

Age: 30 years
Gender: Male

There is a nonenhancing intra-axial T1 hypointense/T2 & FLAIR hyperintense lesion centered on the left parietal operculum in the superficial subcortical and juxtacortical white matter. The lesion consists of groups of several nodules, especially along its internal margin. There is no cortical involvement. There is no diffusion restriction and no mass effect.

The intracranial appearances are otherwise unremarkable.

Case Discussion

The findings are in keeping with multivacuolating neuronal tumor (MVNT). The appearance of MVNT on MRI is virtually pathognomonic. As such, there is no histology to confirm the diagnosis. Follow-up with MRI was recommended.

The parietal lobe is the most common location according to one series (27%) 1.

Case courtesy of Dr Laughlin Dawes

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