Multiple cauda equina schwannomas in neurofibromatosis type 2

Case contributed by A.Prof Frank Gaillard


Previous acoustic schwannoma.

Patient Data

Age: 30 years

The cauda equina demonstrate innumerable enhancing nodules along its entire length, the largest of which is located behind L4 and is vividly enhancing, consistent with a schwannoma. It occupies the vast majority of the canal at this level, compressing the nerve roots around its periphery.

Case Discussion

The patient, who has an established diagnosis of NF2, went on to have surgery for the largest L4 level lesion. 


MICROSCOPIC DESCRIPTION: Paraffin sections show fragments of a moderately hypercellular neurilemmoma (Schwannoma). This is composed of predominantly of Antoni A type tissue in which there are occasional poorly formed Verocay bodies. Tumor cells show mild nuclear pleomorphism. No mitotic figures, densely hypercellular areas or areas of necrosis are identified.

FINAL DIAGNOSIS: Spinal schwannoma

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Case information

rID: 44974
Published: 8th Jun 2016
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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