Presentation
Known history of NF2. Previous cerebral surgery for a tumor resection.
Patient Data
All the lesions are stable compared to the previous MRI. Multiple extra-axial solid tumors at strongly suggest meningiomas are again identified in: the right CPA protruding over the ipsilateral VII and VIII cranial nerves, adjacent to the tentorium on the left, in the left occipital, occipito-parietal and parietal regions, and in the left middle cranial fossa. The left solid nodule within the vestibulocochlear nerve can represent a schwannoma.
Case Discussion
Neurofibromatosis type 2 is a rare autosomal dominant phakomatosis manifesting as development of multiple CNS tumors. Unlike neurofibromatosis type 1 (NF1), it is not associated with neurofibromas. Instead, patients with this disease have:
- intracranial schwannoma(s): mostly vestibular schwannoma(s)
- intracranial and spinal meningioma(s)
- intraspinal-intramedullary ependymoma(s)