Presentation
Patient complaining of progressive clumsiness and lack of coordination. Numbness of lower limbs.
Patient Data
Age: 35 years
Gender: Female
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MRI images demonstrate multiple T2/FLAIR hyperintensities scattered through the infra and supratentorial white-matter, including perpendicular and perivenular periventricular distribution (Dawson's fingers), callososeptal interface, pons and a left superior temporal gyrus juxtacortical focus that demonstrate enhancement.
Case Discussion
Those MRI findings fulfill all the McDonald criteria for the diagnosis of multiple sclerosis:
- dissemination in space (two or more of the following locations):
- periventricular
- juxtacortical
- infratentorial
- spinal cord
- dissemination in time: presence of an asymptomatic enhancing lesion