Multiple sclerosis

Case contributed by Bruno Di Muzio
Diagnosis certain

Presentation

Patient complaining of progressive clumsiness and lack of coordination. Numbness of lower limbs.

Patient Data

Age: 35 years
Gender: Female

MRI Brain

mri

MRI images demonstrate multiple T2/FLAIR hyperintensities scattered through the infra and supratentorial white-matter, including perpendicular and perivenular periventricular distribution (Dawson's fingers), callososeptal interface, pons and a left superior temporal gyrus juxtacortical focus that demonstrate enhancement. 

Case Discussion

Those MRI findings fulfill all the McDonald criteria for the diagnosis of multiple sclerosis

  • dissemination in space (two or more of the following locations):
  • dissemination in time: presence of an asymptomatic enhancing lesion 

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