Multiple sclerosis: advanced

Case contributed by Dr Henry Knipe

Presentation

Leg weakness. No previous imaging available for comparison.

Patient Data

Age: 42
Gender: Female
mri

Multi-focal areas of infra- and supra-tentorial high T2/FLAIR signal predominantly within the supratentorial white matter, with characteristic Dawson's fingers. Further high T2/FLAIR signal foci are noted with the splenium of the corpus callosum, left midbrain, left cerebellar hemisphere. There are juxta-cortical lesions in the left parietal and occipital lobes. A few lesions demonstrated restricted diffusion in the left parietal lobe and right periventricular white matter.

Generalized cerebral atrophy, thinning of the corpus callosum and ventriculomegaly.

No intra or extra-axial collection, mass or areas of susceptibility artefact.

Conclusion:

Extensive high T2/FLAIR changes and volume loss in keeping with advanced of multiple sclerosis.

Case Discussion

The patient has a known history of multiple sclerosis. 

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.