Multiple system atrophy

Case contributed by Huda B. Gharbia
Diagnosis almost certain

Presentation

Ataxia and spasticity.

Patient Data

Age: 70 years
Gender: Female
mri

The pons has reduced volume with prominence of the prepontine cistern and fourth ventricle. The hot cross bun sign is present in the pons on FLAIR and T2-weighted images.

Diffuse widening of folia in both cerebellar hemispheres and the vermis and thinning and increased signal of both middle cerebellar peduncles. Relatively preserved cerebral hemispheric volume.

Case Discussion

Atrophy of cerebrum, cerebellum, and brainstem, with hot cross bun sign of the pons, suggetsive of multiple system atrophy.

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