Myxoid liposarcoma - soft tissues

Case contributed by Ammar Haouimi
Diagnosis almost certain


Painless swelling of the anterior aspect of the right thigh.

Patient Data

Age: 65 years
Gender: Male

There is a large relatively well-circumscribed intramuscular mass centered on the vastus intermedius muscle (measuring 120 x 95 x 70 mm) with no fatty interface with the femoral cortex. It displays a low signal with areas slight high signal to the muscles on T1, very high T2 with hypointense internal septae and areas of restricted diffusion. The post-contrast dynamic sequences show a progressive and heterogeneous enhancement. Normal thickness and signal intensity of the femoral cortex with homogeneous bone marrow. edematous infiltration of the vastus medialis muscle.

Right inguinoscrotal hernia containing mesenteric fat as well as a small bowel loop.

Case Discussion

MRI features of an intramuscular soft tissue tumor centered on the vastus intermedius histologically proven as a myxoid liposarcoma.

Myxoid liposarcoma is considered the second most common subtype of liposarcoma. It occurs most commonly in the lower extremity, particularly the thigh as in this case.


Additional contributor: ZE: Boudiaf, MD, CHU, Constantine, Algeria

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