Myxopapillary ependymoma
Diagnosis certain
Updates to Case Attributes
Body
was changed:
- Based on the MRI features, the lesion is likely a myxopapillary ependymoma of the conus/filum terminale. Other possible differential diagnosis includes intradural metastases (in view of past history of testicular seminoma), schwannoma and meningioma.
- Procedure: Resection of spinal tumor. Microscopic Description: The tumor consists of monomorphic round to elongated cells with fine chromatin. The tumor cells are arranged around vascular cores with fibrillary acellular zone. The tumor also has a papillary architecture with intervening myxoid material. Some areas show coagulative necrosis.
Immunohistochemistry: GFAP (6F2) is positive and EMA (E29) is negative.
Diagnosis: Myxopapillary ependymoma (WHO grade II).
Re-staging CT chest, abdomen & pelvis and tumor markers (AFP, B-HCG & LDH) (for the past history of testicular seminoma were negative.
-<li>Based on the MRI features, the lesion is likely a <a title="Myxopapillary ependymoma" href="/articles/myxopapillary-ependymoma-1">myxopapillary</a> <a title="Myxopapillary ependymoma" href="/articles/myxopapillary-ependymoma-1">ependymoma</a> of the <a title="Conus medullaris" href="/articles/conus-medullaris">conus</a>/<a title="Filum terminale" href="/articles/filum-terminale">filum terminale</a>. Other possible differential diagnosis includes <a title="Intradural extramedullary metastases" href="/articles/intradural-extramedullary-metastases">intradural</a> metastases (in view of past history of testicular seminoma), <a title="Schwannoma - general" href="/articles/schwannoma">schwannoma </a>and <a title="Meningioma of spinal cord" href="/articles/spinal-meningioma">meningioma</a>. </li>- +<li>Based on the MRI features, the lesion is likely a <a href="/articles/myxopapillary-ependymoma-1">myxopapillary</a> <a href="/articles/myxopapillary-ependymoma-1">ependymoma</a> of the <a href="/articles/conus-medullaris">conus</a>/<a href="/articles/filum-terminale">filum terminale</a>. Other possible differential diagnosis includes <a href="/articles/intradural-extramedullary-metastases">intradural</a> metastases (in view of past history of testicular seminoma), <a href="/articles/schwannoma">schwannoma </a>and <a href="/articles/spinal-meningioma">meningioma</a>. </li>
-<li><p>Diagnosis: <a title="Myxopapillary ependymoma" href="/articles/myxopapillary-ependymoma-1">Myxopapillary ependymoma</a> (WHO grade II). </p></li>- +<li><p>Diagnosis: <a href="/articles/myxopapillary-ependymoma-1">Myxopapillary ependymoma</a> (WHO grade II). </p></li>
- +<li><p>Re-staging CT chest, abdomen & pelvis and tumor markers (AFP, B-HCG & LDH) (for the past history of testicular seminoma were negative. </p></li>