Myxopapillary ependymoma

Case contributed by Frank Gaillard


8 month history of low back pain radiating down right leg.

Patient Data

Age: 55 years
Gender: Male

MRI lumbar spine


A large ovoid high T2 low T1 mass is located just below the conus. It demonstrates vivid contrast enhancement. Further enhancing deposits are located in the thecal cul de sac. 

MICROSCOPIC DESCRIPTION: The sections show a moderately cellular tumor, forming perivascular pseudorosettes. The tumor cells form cuffs around blood vessels. There is mucoid material in-between the blood vessels and the tumor cells. The tumor cells have mildly enlarged round nuclei and small nucleoli. No mitoses are seen. There is no endothelial cell hyperplasia or necrosis. The features are those of myxopapillary ependymoma.

FINAL DIAGNOSIS: Myxopapillary ependymoma (WHO Grade I). 

Case Discussion

Typical appearances of a myxopapillary ependymoma, with drop metastases. 

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