Nasopharyngeal carcinoma (recurrent)

Case contributed by Frank Gaillard


Nasopharyngeal carcinoma treated with radiotherapy 10 years earlier with complete remission. Presented with nasal congestion.

Patient Data

Age: 40 years
Gender: Female

CT sinuses


Large mass centered in the sphenoid sinus, bulging into the nasopharynx, with bony destruction. The mass erodes through the clivus and into the pituitary fossa.

Case Discussion

This patient went on to have a biopsy of the mass though the left nasal cavity. 

FINDINGS: Undifferentiated carcinoma.  The biopsy shows an undifferentiated carcinoma associated with an extensive plasmacytic infiltrate. The morphology of the tumor is consistent with the recurrence of nasopharyngeal carcinoma. Tumors with this morphology may also occur as a primary in the nasal cavity. Correlation with the clinical findings is recommended.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.