Neurofibromatosis: unidentified bright objects (UBOs) or focal abnormal signal intensitensity (FASI) lesions

Case contributed by Dr Mohammad A. ElBeialy


Skin lesions. No neurological symptoms.

Patient Data

Age: 4 years
Gender: Female

Multiple T2 and FLAIR hyperintense lesions are seen in the brain stem and the medial cerebellar hemispheres. These lesions are T1 and DWI isointense with no significant post-contrast enhancement. No definite lesions are seen in the basal ganglia, thalami or cerebral white matter.  

Case Discussion

This is a case of neurofibromatosis; one of the phakomatosis (with cafe-au-lait skin lesions and axillary freckling) showing typical focal abnormal signal intensity (FASI) or unidentified bright objects (UBOs) lesions.

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Case information

rID: 38463
Case created: 21st Jul 2015
Last edited: 17th Dec 2016
Inclusion in quiz mode: Included

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