Neurofibromatosis: unidentified bright objects (UBOs) or focal abnormal signal intensitensity (FASI) lesions

Case contributed by Dr Mohammad A. ElBeialy


Skin lesions. No neurological symptoms.

Patient Data

Age: 4 years
Gender: Female

Multiple T2 and FLAIR hyperintense lesions are seen in the brain stem and the medial cerebellar hemispheres. These lesions are T1 and DWI isointense with no significant post-contrast enhancement. No definite lesions are seen in the basal ganglia, thalami or cerebral white matter.  

Case Discussion

This is a case of neurofibromatosis; one of the phakomatosis (with cafe-au-lait skin lesions and axillary freckling) showing typical focal abnormal signal intensity (FASI) or unidentified bright objects (UBOs) lesions.

PlayAdd to Share

Case information

rID: 38463
Published: 26th Jul 2015
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.