Neutropaenic typhlitis

Case contributed by Dr Kirsten Kind

Presentation

50 year old male presented with neutropenic sepsis after several months therapy with sulfasalazine for rheumatoid arthritis. He responded well to gentamicin and Tazocin but became tachycardic and pyrexial again when these were stopped after 5 days. He had no positive cultures and no localizing symptoms so was scanned as a pyrexia of unknown origin.

Patient Data

Age: 50 years
Gender: Male
CT

Thickened descending colon and cecum with minor fat stranding. 

Case Discussion

These findings in a neutropaenic patient are in keeping with neutropaenic typhlitis.

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