Nodular fasciitis

Case contributed by Henry Knipe


Growing neck lump.

Patient Data

Age: 30 years
Gender: Male

Enhancing mass lesion measuring located at the posterior edge of the left sternocleidomastoid muscle. No enlarged cervical lymph nodes. Remainder of the neck is unremarkable.


Appearing within the posterior aspect of the left sternocleidomastoid muscle is a hypoechoic nodular lesion that does not show Doppler signal. 

The patient underwent ultrasound guided core biopsy. 


MICROSCOPIC DESCRIPTION: Sections show a diffusely cellular lesion comprised of uniform bland spindle cells with plump nuclei arranged in loose fasicles and storiform patterns. The cells are set in a background of thick eosinophilic collagen bundles. The stroma also shows focal myxoid appearance. Occasional trapped skeletal muscle cells are seen, and there are scant extravasated lymphocytes and erythrocytes. Mitoses and necrosis are not seen. A small amount of skeletal muscle is present in the biopsy, and the cellular lesion focally involves the muscle. By immunohistochemistry the spindle cells are positive for SMA and negative for S100, Desmin, and CD34.

DIAGNOSIS: Nodular fasciitis.

Case Discussion

Nodular fasciitis is an uncommon, non-neoplastic condition that occurs throughout the body. It usually manifests as a quickly growing, tender lump. 

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.