Nodular fasciitis
Updates to Case Attributes
This case is a good example of how some benign osseous processes can mimic malignancy.
The initial images show an exophytic calcified mass and there was initially a concern for malignancies such as parosteal osteosarcoma or periosteal chondrosarcoma.
On biopsy however, no malignancy was found, and the mass has decreased in size over time. The overall appearance and presentation is compatible with nodular fasciitis.
-<p>This case is a good example of how some benign osseous processes can mimic malignancy.</p><p>The initial images show an exophytic calcified mass and there was initially a concern for malignancies such as parosteal osteosarcoma or periosteal chondrosarcoma.</p><p>On biopsy however, no malignancy was found, and the mass has decreased in size over time. The overall appearance and presentation is compatible with <a title="Nodular fasciitis" href="/articles/nodular-fasciitis">nodular fasciitis</a>.</p>- +<p>This case is a good example of how some benign osseous processes can mimic malignancy.</p><p>The initial images show an exophytic calcified mass and there was initially a concern for malignancies such as parosteal osteosarcoma or periosteal chondrosarcoma.</p><p>On biopsy however, no malignancy was found, and the mass has decreased in size over time. The overall appearance and presentation is compatible with <a href="/articles/nodular-fasciitis">nodular fasciitis</a>.</p>
Updates to Freetext Attributes
The mass was percutaneously biopsied which revealed "Spindle cell proliferation with metaplastic ossification, favor benign/reactive."
FISH DNA Breakapart Signal Analysis for Detection of USP6 translocation showed positive breakapart signals in a large subset of the lesional spindle cells (50%). The finding implicates translocation involving USP6 and supports the diagnosis of nodular fasciitis with ossification/myositis ossifican or soft tissue ABC.
Follow up imaging was recommended.
Updates to Study Attributes
The mass has decreased in size over the three months.
Image X-ray (External rotation) ( update )
Image X-ray (External rotation -- zoomed) ( update )
Image 1 X-ray (External rotation) ( create )
Image 2 X-ray (External rotation -- zoomed) ( create )
Updates to Study Attributes
Normal - no mass two months prior.
Image ( update )
