Non-ossifying fibroma

Case contributed by Dr Jheferson Contreras Grande


Patient with history of trauma. X-rays of the knee showed a lesion in the distal femur.

Patient Data

Age: 14 years
Gender: Female

Multilobular juxtacortical well-defined lytic lesion in distal metaphysis/diaphysis of left femur. It measures 47 x 34 x 18 mm and has a surrounding sclerotic rim. The soft tissues are preserved. Findings are compatible with non-ossifying fibroma.

Pathology Report

Macroscopic findings:

  • Bone tumor of distal femur was received, multiple fragments of bone tissue in 6 milliliter volume. Representative sample was included

Microscopic findings:

  • Non-ossifying fibroma

Case Discussion

Some authors believe that the radiological characteristics of non-ossifying fibroma are pathognomonic and diagnosis does not require any histopathological proof. However, in this case, despite the CT findings, the surgeons decided to pursue invasive biopsy which confirmed a non-ossifying fibroma.

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Case information

rID: 61504
Published: 12th Jul 2018
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included
Excluded from licensing
Institution: Hospital Nacional Edgardo Rebagliati Martins

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