Non-specific interstitial pneumonia

Case contributed by Dr Hani Makky Al Salam

Presentation

Known case of a chronic illness, presented with shortness of breath.

Patient Data

Age: 25 years
Gender: Female

Chest radiograph shows no significant abnormality. 

Bilaterally symmetrical fine reticular opacities with relative subpleural sparing, microcystic abnormalities and mild ground glass opacities with lower lobe predominance.

Case Discussion

There is a well known association of NSIP with SLE. In NSIP, fine reticular opacities and microcystic honeycombing represent fibosis while ground glass opacities without traction bronchiectatic changes possibly represent inflammation. It can be normal in early stage of disease and in plain radiographs.

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