Non-specific interstitial pneumonia

Presentation

Dyspnea and pleuritic chest pain on background of interstitial fibrosis

Patient Data

Age: 60 years
Gender: Female

The pulmonary arteries opacify normally without filling defects to a segmental level, no pulmonary emboli detected. 

Extensive interstitial changes with subpleural predominance associated with areas of traction bronchiectasis, consistent with known underlying pulmonary fibrosis. There are also patchy areas of ground-glass opacities throughout the lungs with no definite honeycombing. Associated mediastinal lymphadenopathy. 

The pulmonary arteries, in particular the left pulmonary branch, appears enlarged most consistent with increased right heart pressures. No other abnormalities are identified. 

Case Discussion

The pattern of fibrosis with ground glass opacity and mediastinal lymphadenopathy and without honeycombing favors NSIP over UIP. 

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