Non-specific interstitial pneumonia

Case contributed by Rogério Augusto Lima Guarneri
Diagnosis almost certain


Progressive systemic sclerosis.

Patient Data

Age: 50 years
Gender: Female

Bibasilar symmetric ground glass opacities with reticulation and traction bronchiectasis/bronchiolectasis.

Case Discussion

Nonspecific interstitial pneumonia (NSIP) can be idiopathic or a manifestation of collagen vascular diseases, hypersensitivity pneumonitis and drug-induced lung disease.

HRCT is the best imaging tool for characterization and assessment of disease extent. The main CT findings are: bibasilar ground-glass opacities and reticular opacities associated with traction bronchiectasis/bronchiolectasis, sometimes with subpleural sparing.

It is important to make the distinction from usual interstitial pneumonia, because NSIP has a better prognosis.

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