Non-specific interstitial pneumonia

Case contributed by Dr Yi-Jin Kuok


Pyrexia of unknown origin and breathlessness

Patient Data

Age: 70 years
Gender: Male

There are subpleural fine interstitial thickening and ground glass opacities with relative subpleural sparing.

5 years of immunosuppression (mainly steroids) later

Marked resolution of the ground glass changes but persistent mild peripheral reticular changes. Note right lower lobe resection staples

Case Discussion

Non-specific interstitial pneumonia (NSIP) responds to steroids, in contrast to usual interstitial pneumonia (UIP).

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