Non-specific interstitial pneumonia (NSIP)

Case contributed by Fazel Rahman Faizi
Diagnosis almost certain

Presentation

Chronic dyspnea and cough

Patient Data

Age: 60 years
Gender: Male

Ground-glass haziness, reticular opacities with traction bronchiectasis (and bronchiolectasis) are noted in both lungs, predominantly in the basal segments. Some degree of volume loss of the lower lobes is noted. Multiple bullae, generally very small, are noted in the right upper lobe. No convincing honeycombing is seen.

Case Discussion

The features are compatible with the fibrotic type of non-specific interstitial pneumonia (NSIP) pattern. The differential diagnosis for this case is UIP pattern. However, the presence of ground-glass haziness and lack of honeycombing make this diagnosis less likely.

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