Oligoastrocytoma NOS

Case contributed by Dr Lawrence Oh


Past history of low grade glioma resection. Routine MRI follow-up

Patient Data

Age: 30 years
Gender: Female

This MRI brain demonstrates a non-enhancing lesion in the right frontal lobe. Given patient has previous history of low grade glioma, this highly suggests a recurrent tumor.

Case Discussion

The patient had a resection of the tumor and histology showed oligoastrocytoma (NOS).

NOTE: This case predates the 2016 WHO classification of CNS tumor revision. As no 1p19q co-deletion status is available a formal diagnosis cannot be reached and the NOS is therefore used (not otherwise specified) - which is recognized in the current classification for cases where molecular information is unavailable. It should also be noted, that under the new classification both an astrocytic and oligodendroglial component needs to be identified, each with its own molecular markers. True oligoastrocytomas are therefore going to be rare, and this case would most likely be classified as either an astrocytoma or an oligodendroglioma. Given extensive calcification, this is likely to be 1p19q co-deleted and most likely would be classified as an oligodendroglioma. Unfortunately, it is not possible to establish this in this historical case, as such one must fall back on the original histological diagnosis. 

PlayAdd to Share

Case information

rID: 24652
Published: 2nd Sep 2013
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.