Oligoastrocytoma NOS (anaplastic)

Case contributed by A.Prof Frank Gaillard

Presentation

Seizures.

Patient Data

Age: 60 years
Gender: Male
Modality: MRI

The anterior most part of the left superior frontal gyrus demonstrates cortical increase in T2/FLAIR signal and enhancement. No restricted diffusion or calcification.

Case Discussion

The patient went on to have a biopsy which demonstrates an anaplastic oligoastrocytoma (path proven). 

NOTE: This case predates the 2016 WHO classification of CNS tumour revision. As no 1p19q co-deletion status is available a formal diagnosis cannot be reached and the NOS is therefore used (not otherwise specified) - which is recognised in the current classification for cases where molecular information is unavailable. It should also be noted, that under the new classification both an astrocytic and oligodendroglial component needs to be identified, each with its own molecular markers. True oligoastrocytomas are therefore going to be rare, and this case would most likely be classified as either an astrocytoma or an oligodendroglioma.

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Case Information

rID: 7740
Case created: 24th Nov 2009
Last edited: 21st Dec 2016
Inclusion in quiz mode: Included

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