Oligodendroglioma NOS

Case contributed by Radswiki
Modality: CT

Right temporal hypodense space occupying lesion which contains internal central calcifications.

Modality: MRI

Right temporal subcortical space occupying lesion which elicits low signal on T1 and high signal on T2 with flair suppression. Foci of high T1 signal (likely representing calcific foci seen on the CT), The lesion is surrounded by mild perifocal oedema signal, Dilated trapped right temporal horn which is anterior to the fore mentioned lesion.

Case Discussion

Note: This tumour predates the recent (2016) revision WHO classification of CNS tumours, and thus molecular markers (IDH mutation and 1p19q co-deletion) are not available. As such, this tumour would now be classified as oligodendroglioma NOS.

Note: Historically, oligodendrogliomas were considered well-circumscribed tumours, however when defined on the basis of IDH-mutation and 1p19q co-deletion, oligodendrogliomas appear to be a group of tumours with different morphology and recent studies suggest that in fact they have poorly defined borders 1. As such, it is at least possible that this case represents a diffuse astrocytoma according to current classification. 

This case was donated to Radiopaedia.org by Radswiki.net

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Case Information

rID: 11687
Case created: 20th Oct 2010
Last edited: 20th May 2017
Inclusion in quiz mode: Included

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