Oligodendroglioma NOS

Case contributed by Jack Ren

Presentation

Seizure

Patient Data

Age: Adult
MRI

There is a irregular intra-axial lesion with ill defined border locate on right parietal lobe. The lesion is heterogeneous in nature & showing low T1 signal with high T2 signal.  The lesion is not enhanced by the contrast.

The is no diffuse restriction on DWI signal. There is a increase signal on ADC suggestive of previous infarction.

There is no evidence of oedema nor mass effect.

Case Discussion

The patient went on to have biopsy of the tumour

Histology

Microscopic Description:  Sections show small pieces of brain tissue infiltrated by a moderately cellular glial tumour displaying oligodendroglial characteristics. Histologic features associated with high-grade, such as tumour necrosis, vascular neogenesis, or elevated mitotic activity, are not seen, although these fragments are very small.

Final Diagnosis: Oligodendroglioma.

Note: This case predates the recent (2016) revision WHO classification of CNS tumours, and thus molecular markers (IDH mutation and 1p19q co-deletion) are not available. As such, this tumour would now be classified as an oligodendroglioma NOS.

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Case information

rID: 24891
Case created: 18th Sep 2013
Last edited: 20th May 2017
Inclusion in quiz mode: Included

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