Presentation
Recurrence of headache and seizure one year after resection of a known brain tumor.
Patient Data
Post-treatment changes including right frontal bone craniotomy and frontal lobe superior gyrus encephalomalacia are seen.
Areas of T2/FLAIR hyperintensity around the encephalomalacia region (mixture of edema and tumor) associated with an abnormal enhancing lesion located at the inferior part of encephalomalacia also is present.
Case Discussion
The recent patient was a known pathologically proven case of oligodendroglioma (WHO grade III) and underwent surgical resection of the tumor one year ago. The patient was referred to us with the recurrence of the clinical symptoms as a headache and seizure.
Microscopy: Neoplastic component composed of loosely cohesive cells with round irregular border nuclei and clear to acidophilic cytoplasm in a rather fibrillary background and presence of a network of thin-walled vessels. Described cells are accentuated around the neurons. mitotic figures some of them with atypical features and 6 per 10 HPF.