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Osmotic demyelination syndrome

Case contributed by Dr Paresh K Desai


60 year old female patient - suspected of "Metabolic Encephalopathy"

Patient Data

Age: 60
Gender: Female


Case Discussion

MRI brain reveals central pontine hyperintensity on T2/ FLAIR.

In addition there is symmetric hyperintensity of the thalami and caudate nuclei and the lentiforms.

MRI Diagnosis is  - Osmotic Demyelination Syndrome (Central pontine and Extra-pontine Myelinolysis).

Cerebellum and the rest of the cortex and subcortical white matter is normal.

Patient was detected to be having hyponatremia with subsequent correction 2 weeks ago.

There is no diffusion restriction.

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Case information

rID: 13133
Published: 5th Mar 2011
Last edited: 13th Aug 2019
Inclusion in quiz mode: Included

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