Osmotic demyelination syndrome

Case contributed by Tom Elswood
Diagnosis almost certain

Presentation

Recently admitted to high dependency unit with severe hyponatremia. Sodium was corrected over 7 days from 100 to 136. Drowsy, dropping sats, recent fall.

Patient Data

Age: 45 years
Gender: Male

Rounded, central low density area in the pons is relatively well demarcated and measures 2.6 cm x 2.2 cm. No evidence of intracranial bleed. No extra-axial hemorrhage. No significant mass effect.  Ventricular system and basal cisterns remain within normal limits. 

Conclusion: low density change in the pons. Consistent with osmotic demyelination, given the patient's history and presentation.

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