Osteogenesis imperfecta and bisphosphonate lines
Case contributed by Michael Sargent
Diagnosis certain
Citation, DOI & case data
Citation:
Sargent M, Osteogenesis imperfecta and bisphosphonate lines. Case study, Radiopaedia.org (Accessed on 04 Feb 2023) https://doi.org/10.53347/rID-6037
Permalink:
rID:
6037
Revisions:
14 times by 5 users - see full revision history
Published:
10th Apr 2009
Systems:
Inclusion in quiz mode:
Included
Patient Data
Age: 10 months
Gender: Female
From the case:
Osteogenesis imperfecta and bisphosphonate lines
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Frontal
Osteopaenic, gracile bones with zebra stripes. Evidence of prior right femoral fracture.
Zebra stripes from cyclical bisphosphonate therapy.
Lateral x-ray of the skull shows wormian bones.
Case Discussion
Baby girl with type II osteogenesis imperfecta, treated with cyclical bisphosphonate therapy (pamidronate) resulting in the "zebra stripe sign". Also note the wormian bones on the skull x-ray.
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