Presentation
Cough and history of acute pulmonary edema.
Patient Data
Age: 60 years
Gender: Female
From the case:
Osteopetrosis
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Considerable cardiomegaly.
Lungs and pleural spaces clear with no features of APO.
Extensive sclerosis affecting all visible bones.
Case Discussion
The sandwich vertebral body sign is apparent. This can be mistaken for the rugger-jersey sign (associated with hyperparathyroidism) which appears less dense and less defined, or the picture frame vertebral body which also involves the lateral margins.
This patient had a prior confirmed diagnosis of autosomal dominant type 2 osteopetrosis and also suffers from associated pancytopenia and splenomegaly.