Osteoradionecrosis of the mandible
Patient received radiotherapy for head and neck carcinoma.
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Right hemimandible shows a lytic destruction.
Osteoradionecrosis following radiotherapy for head and neck SCC.
Three irregularly shaped fragments of mandible bone, one measuring 70x40x9mm and including ramus and head and neck of mandible, a triangular fragment 50x28x8mm and an irregularly shaped fragment 8x30x10mm including two attached teeth. The edges of each fragment are focally irregular and congested.
Sections of the 3 bone fragments show the two larger ones to be viable bone with a vascularised marrow space and vascular fibrous tissue is seen on one end of both of them. Within the fibrous tissue, there are fragments of bone. The smallest fragment is non-viable, consistent with being osteoradionecrosis. There is some vascularisation of marrow spaces at one end of the fragment.
Right mandible: Viable bone and nonviable bone, consistent with being osteoradionecrosis. The viable bone shows revascularisation.