Ovarian fibroma

Case contributed by Dr Fadi Aidi


Non specific pelvic pain and feeling of pelvic fullness. No gynecologic symptoms. No past medical or surgical history.

Patient Data

Age: 35 years
Gender: Female

There is a well-defined oval shape homogenous left adnexal lesion with adjacent ovarian follicles suggestive of ovarian origin of the lesion, the lesion appears solid without cystic component, no fat or blood elements. It appears isointense on T1 and hypointense on T2. Diffuse hyperintense signal seen on STIR images representing edema. The lesion measures about 6.5x6x5.5 cm. Delayed homogenous enhancement is noted.

Features are likely representing benign left ovarian lesion with fibrous component (fibroma most likely). Differential diagnoses include broad ligament/large pedunculated uterine fibroid , however less likely.

The uterus has normal internal structure. Normal right ovary.

Normal urinary bladder. Mild amount of pelvic free fluid.

There is no apparent lymphadenopathy.

The femoral heads are normally shaped and articulate normally with the acetabula. They have normal bone- marrow signal characteristics.

Histopathology Report

Gross Examination

Specimen received fixed in formalin solution, labeled with patient's name, consists of 4.5x3 cm ovarian tissue with attached 7x4.5x4.5 cm oval relatively circumscribed mass. On cutting the ovarian tissue is cystic and the cut surface of the mass is white tan in color and fibrotic. Multiple representative sections submitted and embedded in seven cassettes.

Microscopic Examination

Serial levels reveal an ovarian tumor composed of closely packed spindle stromal cells arranged in storiform pattern of growth. Hyaline bands are present centered mainly around blood vessels. Areas of edema also detected. Cellular atypia is almost minimal and mitotic activity is also almost abscent. No necrosis. The overall picture is consistent with fibroma. The attached ovarian tissue is unremarkable and contains few cystic follicles, dilated vascular channels and two corpus luteal cysts.

Final Diagnosis


-         FlBROMA.

Case Discussion

Ovarian fibroma is a benign stromal/sex cord tumor and the commonest in this category. Middle age female more commonly affected. The tumor size can be large at presentation as in this case. Many associations are known with this tumor like Meigs and Gorlin-Goltz syndromes. On ultrasound, it appears hypoechoic with acoustic shadowing even without calcifications. On MRI, it has low T2 signal which considered characteristic feature of fibrous-origin tumors. On imaging, it can resemble large pedunculated subserosal uterine leiomyoma.

PlayAdd to Share

Case information

rID: 83863
Published: 12th Nov 2020
Last edited: 12th Nov 2020
System: Gynaecology
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.