Ovarian yolk sac tumor

Case contributed by Yahya Baba
Diagnosis almost certain

Presentation

Abdominal lump with a pelvic mass on ultrasound. Tumor markers show elevated alpha-fetoprotein (AFP) and no beta-hCG secretion. MRI for further assessment.

Patient Data

Age: 12 months
Gender: Female
mri
  • well-margined bulky pelvic solid mass, located between the urinary bladder and the rectum, arising either from the superior vaginal part or from the ovaries. This mass is T1 isointense (compared to muscle), and T2 hyperintense, measuring 62 x 54 mm on axial images and 61 mm on coronal images.

  • it demonstrates a vivid heterogeneous enhancement after Gadolinium injection.

  • marked ureteral and pelvicalyceal dilatation upstream of the pelvic mass

  • the uterus is present, of normal size considering the age, and looks unremarkable

  • there is no obvious rectal or urinary bladder extension

  • this mass is in close contact with the iliac vessels.

  • the ovaries are not seen

  • there is no lymphadenopathy nor ascites

Case Discussion

Features of a pelvic mass (of probable ovarian origin) with elevated AFP. In this case, the differentials include yolk sac tumor, ovarian embryonal carcinoma, and immature teratomas.

The patient was operated on and pathology confirmed an ovarian yolk sac tumor.

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