Pallidodentate calcinosis

Case contributed by Dr Varun Babu


Acute onset left sided paresis.

Patient Data

Age: 75 years
Gender: Female

Intracranial calcification identified in 

  1. pineal gland
  2. choroid plexus
  3. globus pallidus
  4. dentate nucleus
  5. bilateral cavernous ICA

Three years later

Progression in density of calcifications.


10 years later

More distinct calcification of the aforementioned areas. 

Case Discussion

Striatopallidodentate nuclei are a common site of deposition of lot of elements including iron, calcium, manganese and nowadays even gadolinium. As radiologists we have a tendency to report most of the cases as Fahr disease, whilst the underlying etiology could be one of many underlying causes.

In fact Parkinsonism is one of the most common clinical presentations of mineral deposition in these sites. 

This series of CT studies done over a period of ten years shows the progressive age related nature of increased deposition of minerals in the brain. 

The turn of this decade is currently interested in Gadolinium deposition in the brain and yet again - these are its favorite sites of deposition. 


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Case information

rID: 47868
Published: 7th Sep 2016
Last edited: 3rd Nov 2017
Inclusion in quiz mode: Included

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