Pan-lobular emphysema due to alpha-1-antitrypsin deficiency

Case contributed by Dr Jeremy Jones


49 year old male with severe breathlessness and recurrent infections

Patient Data

Age: 50
Gender: Male



Case Discussion

Pan-lobular emphysema with characteristic basal predominance. Severe destruction of the basal segments.  Widespread tracheal diverticulae that extend into the lower bronchial tree - associated with severe emphysema.

Subsequent investigation confirmed alpha-1-antitrypsin deficiency.

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Case information

rID: 13441
Published: 12th Apr 2011
Last edited: 24th Mar 2019
System: Chest
Inclusion in quiz mode: Included

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